XTANDI is a prescription medicine used to treat men with prostate cancer that:

  • no longer responds to a hormone therapy or surgical treatment to lower testosterone
  • OR

  • has spread to other parts of the body and responds to a hormone therapy or surgical treatment to lower testosterone

It is not known if XTANDI is safe and effective in females or children.

XTANDI frequently asked questions

Search below to find answers to frequently asked questions.

What is enzalutamide?

Enzalutamide is the generic name for XTANDI.

What is XTANDI (enzalutamide)?

XTANDI is a prescription medicine used to
treat men with prostate cancer that:

  • no longer responds to a hormone therapy or
    surgical treatment to lower testosterone

    OR

  • has spread to other parts of the body and
    responds to a hormone therapy or surgical
    treatment to lower testosterone

It is not known if XTANDI is safe and effective
in females or children.
See how XTANDI may help.

Who is XTANDI (enzalutamide) for?

XTANDI is for men with prostate cancer that:

  • no longer responds to a hormone therapy or
    surgical treatment to lower testosterone

    OR

  • has spread to other parts of the body and
    responds to a hormone therapy or surgical
    treatment to lower testosterone

It is not known if XTANDI is safe and effective
in females or children.
See how XTANDI may help.

What types of prostate cancer does
XTANDI treat?

XTANDI is a prescription medicine that is FDA
approved to treat 3 types of prostate cancer:

  • Non-metastatic castration-resistant
    prostate cancer (nmCRPC): prostate cancer
    that has not spread to other parts of the
    body and no longer responds to treatment
    to lower testosterone.
    Learn more about nmCRPC
  • Metastatic castration-sensitive prostate
    cancer (mCSPC): prostate cancer that has
    spread to other parts of the body and
    responds to treatment to lower
    testosterone.
    Learn more about mCSPC
  • Metastatic castration-resistant prostate
    cancer (mCRPC): prostate cancer that has
    spread to other parts of the body and
    no longer responds to treatment to lower
    testosterone.
    Learn more about mCRPC

What are androgen receptor inhibitors?

Androgen receptor inhibitors (also called
antiandrogens or androgen receptor
antagonists) are a class of drugs that are
used to help keep prostate cancer cells from
growing. They act by inhibiting androgen
hormones, such as testosterone.
See how XTANDI works.

How does XTANDI (enzalutamide)
work?

XTANDI is an androgen receptor inhibitor. XTANDI is thought to work by interfering with the connection between androgens (a group of hormones that includes testosterone) and androgen receptors. This can help slow cancer cell growth. This is how XTANDI was shown to work in laboratory studies. Clinical significance is unknown.
See how XTANDI works.

What is the dosing and administration
for XTANDI?

In clinical trials, XTANDI was taken by mouth
as four 40-mg capsules (160 mg total) once a
day.
See how to take XTANDI.

How do I take XTANDI?

Take XTANDI exactly as your doctor tells you.
Take your prescribed dose once a day, at the
same time each day. Your doctor may change
your dose if needed.
See how to take XTANDI.

Do I need to take XTANDI with food?

XTANDI can be taken with or without food.
See how to take XTANDI.

What are the most common side effects
of XTANDI?

The most common side effects of XTANDI
include:

  • Weakness or feeling more tired than usual
  • Back pain
  • Hot flashes
  • Constipation
  • Joint pain
  • Decreased appetite
  • Diarrhea
  • High blood pressure

XTANDI may cause serious side effects.
See a full list of serious side effects.

How do I get XTANDI?

XTANDI is a prescription medicine that you can get through a specialty pharmacy or the pharmacyXTANDI is a prescription medicine that you
can get through a specialty pharmacy or the
pharmacy in your doctor’s office.
Find out how to get XTANDI.
in your doctor’s office.
Find out how to get XTANDI.

Are there ways to help pay for XTANDI?

If you need help paying for XTANDI, call
XTANDI Support SolutionsSM at
1-855-8XTANDI (1-855-898-2634) to speak to
an access specialist who can help you find
ways to pay for XTANDI.
Learn more about XTANDI Support Solutions.
Learn more about XTANDI Support Solutions.

If you need help paying for XTANDI, call XTANDI Support SolutionsSM at 1-855-8XTANDI
(1-855-898-2634) to speak to an access specialist who can help you find ways to pay for XTANDI. Learn more about XTANDI Support Solutions.

Important Safety
Information

Important Safety Information and Indication

What is XTANDI?

XTANDI is a prescription medicine used to treat men with prostate cancer that:

It is not known if XTANDI is safe and effective in females or children.

Important Safety Information

What should I tell my doctor before taking XTANDI?

Tell your doctor about all your medical conditions, including if you:

How should I take XTANDI?

What are the possible side effects of XTANDI?

XTANDI may cause serious side effects including:

Your doctor will stop treatment with XTANDI if you have serious side effects.

The most common side effects of XTANDI include:

XTANDI may cause fertility problems in males, which may affect the ability to father children. Talk to your doctor if you have concerns about fertility.

These are not all the possible side effects of XTANDI. For more information, talk to your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

For further information, please talk to your doctor and click here for Patient Information and Full Prescribing Information for XTANDI.

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