Side effects

XTANDI may cause side effects

What are the possible side effects of XTANDI?

XTANDI may cause serious side effects including:

  • Potential side effect of XTANDI: Seizure.

    Seizure

    If you take XTANDI®, you may be at risk of having a seizure. Avoid activities where a sudden loss of consciousness could seriously harm you or someone else. Tell your doctor right away if you lose consciousness or have a seizure.

  • Potential side effect of XTANDI: Posterior Reversible Encephalopathy Syndrome (PRES).

    Posterior Reversible Encephalopathy Syndrome (PRES)

    If you take XTANDI you may be at risk of developing a condition involving the brain called PRES. Tell your doctor right away if you have a seizure or quickly worsening symptoms such as headache, decreased alertness, confusion, reduced eyesight, blurred vision or other visual problems. Your doctor will do a test to check for PRES.

  • Potential side effect of XTANDI: Allergic reactions.

    Allergic reactions

    Allergic reactions have happened in people who take XTANDI. Stop taking XTANDI and get medical help right away if you develop swelling of the face, tongue, lips, or throat.

  • Potential side effect of XTANDI: Heart disease.

    Heart disease

    Blockage of the arteries in the heart (ischemic heart disease) that can lead to death has happened in some people during treatment with XTANDI. Your doctor will monitor you for signs and symptoms of heart problems during your treatment. Call your doctor or go to the emergency room right away if you get chest pain or discomfort at rest or with activity or shortness of breath during your treatment with XTANDI.

  • Potential side effect of XTANDI: Falls and bone fractures.

    Falls and bone fractures

    XTANDI treatment may increase your risk for falls and bone fractures. Falls were not caused by loss of consciousness or seizures. Your doctor will monitor your risks for falls and bone fractures during treatment with XTANDI.

  • Your doctor will stop treatment with XTANDI if you have serious side effects.

The most common side effects of XTANDI and general tips that may help

The most common side effects that men experienced in a clinical trial while taking XTANDI are below. You’ll also see information on how to discuss each side effect with your doctor. This information has not been studied with XTANDI.

Remember, the information below does not replace directions from your doctor. Always talk to your healthcare team about side effects and information that may help to address them.

The most common side effects of XTANDI include:

  • Muscle and joint pain

    Write down the pain you experience and share it with your healthcare team. Your doctor may recommend physical therapy or medicine to reduce swelling and help with inflammation. They may also suggest light stretching and hot or cold compresses to help reduce the pain.

  • Feeling more tired than usual

    Talk to your doctor if you experience fatigue. They may recommend daily exercise or other activities that may help reduce exhaustion. Do not start a new exercise routine without direction from your doctor. If you feel tired during the day, it’s okay to rest and take a nap to help increase your energy level.

  • Hot flashes

    Talk to your doctor if you experience hot flashes. They may recommend you try to lower your body’s temperature, along with wearing loose-fitting cotton clothing. Keeping a fan running and your windows open can also help circulate the air throughout your home, which may help.

  • Constipation or decreased appetite

    Tell your doctor if you have constipation or decreased appetite. They may offer you advice about managing your diet, and how you can make adjustments. Work with them to create an eating plan that includes the right amount of nutrients and liquids your body needs. This includes foods you should be eating and foods to avoid.

  • Diarrhea

    Report diarrhea to your doctor right away. Your doctor may suggest you take over-the-counter anti-diarrheal medicine to help, but it’s also important to stay hydrated. Sports drinks, water and bouillon may be recommended.

  • High blood pressure

    Your doctor may examine you and ask you questions about your medical history and symptoms, as well as listen to your heart. They may recommend you make certain lifestyle changes, such as diet and exercise. Your doctor may also recommend certain medicines to help lower your blood pressure.

  • Bleeding problems

    XTANDI may increase your risk of bleeding. Be sure to discuss symptoms of bleeding with your doctor. If you suspect internal bleeding or have external bleeding that won't stop, seek immediate medical attention.

  • Falls and bone fractures

    If you experience a fall, let your doctor know immediately. Your doctor may need to make adjustments to your treatment plan. Your healthcare team may recommend ways to help make your surroundings safer and find ways to reduce your risk of falling. They may suggest equipment to assist you and exercises to improve your safety and balance. Additionally, wearing supportive footwear can help maintain stability and minimize the chances of falls.

  • Headache

    If you encounter persistent headaches, let your doctor know immediately, so they can assess the cause and determine the best course of action to alleviate your pain. While your doctor may recommend specific pain relief medication, activities that reduce stress levels, getting enough sleep, staying hydrated, and reducing caffeine intake may help prevent headaches.

XTANDI may cause fertility problems in males, which may affect the ability to father children. Talk to your doctor if you have concerns about fertility.

These are not all the possible side effects of XTANDI. For more information, talk with your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

For further information, please talk with your doctor and see Patient Information and Full Prescribing Information for XTANDI.

Euvon, an XTANDI patient.

Euvon, an XTANDI patient and proud grandpa

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