XTANDI is a prescription medicine used to treat men with prostate cancer that:
- no longer responds to a hormone therapy or surgical treatment to lower testosterone
- has spread to other parts of the body and responds to a hormone therapy or surgical treatment to lower testosterone
OR
It is not known if XTANDI is safe and effective in females or children.
Taking XTANDI
Take XTANDI exactly as your doctor tells you. Take your prescribed dose once a day, at the same time each day. Your doctor may change your dose if needed.
Do not change or stop taking your prescribed dose of XTANDI without talking with your doctor first.
XTANDI can be taken with or without food.
Swallow XTANDI capsules or tablets whole. Do not chew, dissolve, or open the capsules. Do not cut, crush or chew the tablets.
If you are receiving gonadotropin-releasing hormone (GnRH) therapy, you should continue with this treatment while taking XTANDI unless you have had surgery to lower the amount of testosterone in your body (surgical castration).
What to do if you miss a dose
If you miss a dose of XTANDI, take your prescribed dose as soon as you remember that day. If you missed your daily dose, take your prescribed dose at your regular time the next day. Do not take more than your prescribed dose of XTANDI each day.
If you take too much XTANDI:
- Call your doctor, or
- Go to the emergency room right away
You may have an increased risk of seizure if you take too much XTANDI.
What to tell your doctor before starting XTANDI
Tell your doctor about all your medical conditions, including if you:
- Have a history of seizures, brain injury, stroke, or brain tumors
- Have a history of heart disease, have high blood pressure, or have abnormal amounts of fat or cholesterol in your blood (dyslipidemia)
- Are pregnant or plan to become pregnant. XTANDI can cause harm to your unborn baby and loss of pregnancy (miscarriage)
- Have a partner who is pregnant or may become pregnant
- Males who have female partners who are able to become pregnant should use effective birth control (contraception) during treatment with XTANDI and for 3 months after the last dose
- Males must use a condom during sex with a pregnant female
- Are breastfeeding or plan to breastfeed. It is not known if XTANDI passes into your breast milk
- Take other medicines
XTANDI may affect the way other medicines work, and other medicines may affect how XTANDI works. These include prescription and over-the-counter medicines, vitamins, and herbal supplements. Do not start or stop any medicine without talking to your doctor.
