XTANDI is a prescription medicine used to treat men with prostate cancer that:

  • no longer responds to a hormone therapy or surgical treatment to lower testosterone
  • OR

  • has spread to other parts of the body and responds to a hormone therapy or surgical treatment to lower testosterone

It is not known if XTANDI is safe and effective in females or children.

Ken, a real patient on XTANDI, with Pat, his wife and caregiver.
Ken & Pat

Taking XTANDI


How to take; XTANDI® (enzalutamide) can be taken with or without food

Take XTANDI exactly as your doctor tells you. Take your prescribed dose once a day, at the same time each day. Your doctor may change your dose if needed.

How to take; swallow XTANDI® (enzalutamide) capsules whole

Do not change or stop taking your prescribed dose of XTANDI without talking with your doctor first.

How to take; XTANDI® (enzalutamide)

XTANDI can be taken with or without food.

How to take; swallow XTANDI® (enzalutamide) capsules whole icon

Swallow XTANDI capsules whole. Do not chew, dissolve, or open the XTANDI capsules.

Continue treatment; icon

If you are receiving gonadotropin-releasing hormone (GnRH) therapy, you should continue with this treatment while taking XTANDI unless you have had surgery to lower the amount of testosterone in your body (surgical castration).

What to do if you miss a dose

If you miss a dose of XTANDI, take your prescribed dose as soon as you remember that day. If you missed your daily dose, take XTANDI at your regular time the next day. Do not take more than your prescribed dose in one day.

 

If you take too much XTANDI:

  • Call your doctor
  • Go to the emergency room right away

You may have an increased risk of seizure if you take too much XTANDI.


What to tell your doctor before starting XTANDI

Tell your doctor about all your medical conditions, including if you:

  • Have a history of seizures, brain injury, stroke, or brain tumors
  • Have a history of heart disease, have high blood pressure, or have abnormal amounts of fat or cholesterol in your blood (dyslipidemia)
  • Are pregnant or plan to become pregnant XTANDI can cause harm to your unborn baby and loss of pregnancy (miscarriage)
  • Have a partner who is pregnant or may become pregnant
    • Males who have female partners who are able to become pregnant should use effective birth control (contraception) during treatment with XTANDI and for 3 months after the last dose
    • Males must use a condom during sex with a pregnant female
  • Are breastfeeding or plan to breastfeed. It is not known if XTANDI passes into your breast milk
  • Take other medicines

XTANDI may affect the way other medicines work, and other medicines may affect how XTANDI works. These include prescription and over-the-counter medicines, vitamins, and herbal supplements. Do not start or stop any medicine without talking to your doctor.

Steroids are not required with XTANDI. Talk to your doctor if you have questions about steroids.

Important Safety Information

Important Safety Information and Indication

What is XTANDI?

XTANDI is a prescription medicine used to treat men with prostate cancer that:

It is not known if XTANDI is safe and effective in females or children.

Important Safety Information

What should I tell my doctor before taking XTANDI?

Tell your doctor about all your medical conditions, including if you:

How should I take XTANDI?

What are the possible side effects of XTANDI?

XTANDI may cause serious side effects including:

Your doctor will stop treatment with XTANDI if you have serious side effects.

The most common side effects of XTANDI include:

XTANDI may cause fertility problems in males, which may affect the ability to father children. Talk to your doctor if you have concerns about fertility.

These are not all the possible side effects of XTANDI. For more information, talk to your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

For further information, please talk to your doctor and click here for Patient Information and Full Prescribing Information for XTANDI.

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